Principal Scientist

Company: Regeneron Pharmaceuticals, Inc.
Location: Tarrytown
Posted on: January 30, 2026

Job Description:

We are seeking a highly skilled, motivated, and innovative Principal Scientist to lead the development of therapies to treat hearing loss and vestibular disorders. In this role, you will independently lead research projects and drive the development of novel therapies for inner ear disorders. A typical day in the life of a Principal Scientist on this team may include: Lead the design of rigorous and appropriate experiments to address core questions of hearing biology, that can drive drug discovery and preclinical programs. Develop and characterize novel animal models to better understand mechanisms of hearing loss and evaluate the potential of novel therapeutics to mitigate hearing phenotypes. Design and execute in vivo and in vitro functional assays to understand the mechanisms of syndromic and non-syndromic hearing loss. Work cross-functionally with a team to develop translationally relevant studies. Carefully analyze and evaluate data. Present data both internally and externally, and participate in discussions in our collaborative, cross-functional team environment. Independently draft and review protocols and articles for publication. Motivate, develop, and supervise junior scientists, research associates and other trainees. This role might be for you if: You enjoy a dynamic, fast-paced environment Can work well both independently and in a team, and communicate effectively with colleagues across all levels Maintain a rigorous approach to scientific work You are resilient in overcoming challenges and can adapt to shifting priorities You are excited to learn on the fly and expand your areas of expertise To be considered for this role, you must have the following : Ph.D. with a strong record of innovation and publication and 5 years of experience. Proven expertise in drug development is required. Managerial experience is highly desirable. In vivo experimental experience is desirable. Strong understanding of human and mouse genetics and/or auditory physiology is an advantage. Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We have an inclusive culture that provides comprehensive benefits, which vary by location. In the U.S., benefits may include health and wellness programs (including medical, dental, vision, life, and disability insurance), fitness centers, 401(k) company match, family support benefits, equity awards, annual bonuses, paid time off, and paid leaves (e.g., military and parental leave) for eligible employees at all levels! For additional information about Regeneron benefits in the US, please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other countries specific benefits, please speak to your recruiter. Please be advised that at Regeneron, we believe we are most successful and work best when we are together. For that reason, many of Regenerons roles are required to be performed on-site. Please speak with your recruiter and hiring manager for more information about Regenerons on-site policy and expectations for your role and your location. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business. For roles in which the hired candidate will be working in the U.S., the salary ranges provided are shown in accordance with U.S. law and apply to U.S.-based positions. For roles which will be based in Japan and/or Canada, the salary ranges are shown in accordance with the applicable local law and currency. If you are outside the U.S, Japan or Canada, please speak with your recruiter about salaries and benefits in your location. Please note that certain background checks will form part of the recruitment process. Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc. Salary Range (annually) $128,600.00 - $210,000.00

Keywords: Regeneron Pharmaceuticals, Inc., Stratford , Principal Scientist, Science, Research & Development , Tarrytown, Connecticut